Silver Book reference

NIH Fact Sheet: Stroke

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    • The development of antioxidants that reduce oxidative damage is underway. One antioxidant that has been found, uric acid, has an even greater protective effect when combined with tPA.  
    • New approaches are under development to reduce ischemic stroke damage and other damage occuring because of stroke.  
    • A major objective is to control blood pressure and preempt primary and secondary stroke. Assessing specific antihypertensive therapies will identify specific treatments that will lower blood pressure.  
    • A recent data analysis of more than 2,700 stroke patients from the U.S. and Europe confirmed tPA’s effectiveness, which could save the U.S. nearly $50 million a year.  
    • In 1995, an NIH-funded clinical trial established the first FDA-approved treatment for acute ischemic stroke treatment.The drug tPA, if given within 3 hours of stroke symptoms, reduces the risk of…  
    • 5.5 million Americans have survived a stroke, but live with its impact every day.  
    • The age-adjusted stroke mortality rate has decreased 70% since 1950, and 64% since 1972.