Silver Book Fact

Use of pneumonia vaccine in children reduced rates in adults age 65+

Within a year of introduction of PCV7 (7-valent pneumococcal conjugate vaccine) for use in the U.S. in infants, children under 2 years, and high risk children ages 2 to 4; invasive pneumococcal disease rates in unvaccinated individuals age 65 and older fell by 18%.

Whitney, Cynthia G., Monica M. Farley, James Hadler, Lee H. Harrison, Nancy M. Bennett, et al.; for the Active Bacterial Core Surveillance of the Emerging Infections Program Network. Decline in Invasive Pneumococcal Disease After the Introduction of Protein-Polysaccharide Conjugate Vaccine. N Engl J Med. 2003; 348(18): 1737-46. http://www.nejm.org/doi/full/10.1056/NEJMoa022823

Reference

Title
Decline in Invasive Pneumococcal Disease After the Introduction of Protein-Polysaccharide Conjugate Vaccine
Publication
N Engl J Med
Publication Date
2003
Authors
Whitney, Cynthia G., Monica M. Farley, James Hadler, Lee H. Harrison, Nancy M. Bennett, et al.; for the Active Bacterial Core Surveillance of the Emerging Infections Program Network
Volume & Issue
Volume 348, Issue 18
Pages
1737-46
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Eradication of infectious diseases from vaccination
    Spanning more than 200 years of research and development, 10 infectious diseases have been at least 90 percent eradicated in the United States thanks to vaccines.  
  • Immunization significantly lowers rates of leading infectious diseases
    Impact of Immunization on the Number of Annual Cases of Disease in the USA  
  • Use of shingles vaccines significantly reduced disease burden
    Use of a live attenuated VZV (varicella-zoster vaccine) in a randomized trial reduced the burden of illness from shingles by 61.1% and the incidence of postherpetic neuralgia (PHN) by 66.5%.  
  • Flu vaccine use can reduce illness risk in U.S. by 60%
    Recent studies from the Centers for Disease Control and Prevention show that the influenza vaccine can reduce the risk of illness in the overall U.S. population by around 60%. …  
  • Shingles vaccine reduces incidence by >50%
    Use of a live attenuated VZV (varicella-zoster vaccine) in a randomized trial reduced the incidence of shingles by 51.3%.