Silver Book Fact

Staff flu vaccination reduces incidence of staff and patients

Vaccination of staff in a tertiary care facility over a period of 12 influenza seasons increased vaccination coverage from 4% to 67%, reduced laboratory-confirmed cases of influenza amongst staff from 42% to 9%, and reduced nosocomial cases among hospitalized patients from 32% to 0.

Salgado C, Giannetta E, Hayden F, Farr B. Preventing Nosocomial Influenza by Improving the Vaccine Acceptance Rate of Clinicians. Infect Control Hosp Epidemiol. 2004; 25(11): 923-8.


Preventing Nosocomial Influenza by Improving the Vaccine Acceptance Rate of Clinicians
Infect Control Hosp Epidemiol
Publication Date
Salgado C, Giannetta E, Hayden F, Farr B
Volume & Issue
Volume 25, Issue 11
Read Full Resource


  • Innovative Medical Research
  • Human Value

Related Facts

  • Life years saved from infectious disease eradication
    Infectious disease eradication in the U.S. led to the following annual life years saved (LYS): 5,811,852 for measles 42,702 for tetanus 212,690 for polio 1,685,740 for smallpox  
  • Value of polio eradication
    Eradication of polio is estimated to produce savings to governments of $1.5 billion per year.  
  • Negative value of antibiotics to drug companies
    The value of an antibiotic to a drug company is negative $50 million- compared to the positive value of $1 billion for a new musculoskeletal drug.  
  • Significant savings from zoster vaccine
    In a cost-effectiveness analysis, investigators estimated the zoster vaccine cost $44,000 per quality-adjusted life year saved for a 70-year-old woman.  
  • Infection control program reduced hospital-acquired HAIs by > 1/3
    A multimodal infection control program reduced the rate of hospital-acquired HAIs by more than 1/3 and improved quality of care and patient outcomes.