Silver Book Fact

Identifying individuals at high risk for developing AFib

Using simple bedside measures, identification of individuals at risk for developing atrial fibrillation is feasible. Selecting high-risk individuals for inclusion in atrial fibrillation prevention trials may also enhance prevention strategies.

Schnabel, RB, LM Sullivan, D Levy, MJ Pencina, JM Massaro, RB Dâ??Agostino, C Newton-Cheh, JF Yamamoto, JW Magnani, TM Tadros, WB Kannel, TJ Wang, PT Ellinor, PA Wolf, RS Vasan, and EJ Benjamin. Development of a Risk Score for Atrial Fibrillation (Framingham Heart Study): A community-based cohort study. Lancet. 2009; 373(9665): 739-45. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2809%2960443-8/abstract

Reference

Title
Development of a Risk Score for Atrial Fibrillation (Framingham Heart Study): A community-based cohort study
Publication
Lancet
Publication Date
2009
Authors
Schnabel, RB, LM Sullivan, D Levy, MJ Pencina, JM Massaro, RB Dâ??Agostino, C Newton-Cheh, JF Yamamoto, JW Magnani, TM Tadros, WB Kannel, TJ Wang, PT Ellinor, PA Wolf, RS Vasan, and EJ Benjamin
Volume & Issue
Volume 373, Issue 9665
Pages
739-45
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Cost of warfarin therapy for AFib patients
    In patients with nonvalvular atrial fibrillation (AF) and one additional stroke risk factor, warfarin therapy cost $8,000 per quality-adjusted life-year (QALY) saved.  
  • Stroke prevention through optimal anticoagulation
    If half of atrial fibrillation patients who currently receive warfarin in a routine care setting had their anti-coagulation optimized, around 9,000 strokes and more than 29,000 bleeds would be prevented.  
  • Stroke risk reduction from thrombin inhibitor in AFib patients
    A recently approved direct thrombin inhibitor was found to reduce the risk of stroke/peripheral embolic events in atrial fibrillation patients by 34%, and the risk of hemorrhagic stroke by 74%—compared…  
  • Effect of optimal anticoagulation
    If 50% of atrial fibrillation patients who currently receive warfarin in routine medical care were optimally anticoagulated, 9,852 emboli would be prevented and $1.3 billion would be saved each year.  
  • Stroke rates among Afib patients
    In one year, 58,283 of the 1.265 million Medicare beneficiaries with atrial fibrillation that did not receive prophylaxis suffered a stroke. For those who did receive anti-coagulants, 38,468 suffered strokes.