Silver Book Fact

Flu vaccine use reduces disease burden

Use of the LAIV (live attenuated influenza virus) in healthy adults ages 18 to 64 reduced febrile illness by 19% and upper respiratory tract illnesses by 24%. It also reduced the days of illness by 23% to 27% depending on severity of illness, lost work days by 18% to 28%, and days with visits to health care professionals by 25% to 41%.

Nichol K, Lind A, Karen K, Murdoch M, et al. The Effectiveness of Vaccination Against Influenza in Healthy, Working Adults. NEJM. 1995; 333(14): 889-93. http://www.nejm.org/doi/full/10.1056/NEJM199510053331401

Reference

Title
The Effectiveness of Vaccination Against Influenza in Healthy, Working Adults
Publication
NEJM
Publication Date
1995
Authors
Nichol K, Lind A, Karen K, Murdoch M, et al.
Volume & Issue
Volume 333, Issue 14
Pages
889-93
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Value of smallpox eradication
    An estimated $100 million spent in eradicating smallpox from 1967 to 1977 saved the world around $1.35 billion a year.  
  • Economic value from flu vaccine in elderly
    As over 60% of the economic burden of influenza falls on those ages 65 and older, programs to reduce the impact of influenza on older Americans would have the greatest…  
  • Mortality from vaccine-preventable diseases
    Vaccine-preventable diseases or their complications account for 50,000 to 90,000 adult deaths in the U.S. each year.  
  • Annual flu vaccine could save 275,000 QALYs
    Offering the influenza vaccine annually to all people over the age of 50 would save around 275,000 quality-adjusted life years over the lifetimes of a birth cohort of 4 million.…  
  • Cost effectiveness of MMR vaccine
    For every dollar spent on the MMR (measles, mumps, and rubella) vaccine, $21 is saved.