Silver Book Fact

Flu vaccine use reduces disease burden

Use of the LAIV (live attenuated influenza virus) in healthy adults ages 18 to 64 reduced febrile illness by 19% and upper respiratory tract illnesses by 24%. It also reduced the days of illness by 23% to 27% depending on severity of illness, lost work days by 18% to 28%, and days with visits to health care professionals by 25% to 41%.

Nichol K, Lind A, Karen K, Murdoch M, et al. The Effectiveness of Vaccination Against Influenza in Healthy, Working Adults. NEJM. 1995; 333(14): 889-93. http://www.nejm.org/doi/full/10.1056/NEJM199510053331401

Reference

Title
The Effectiveness of Vaccination Against Influenza in Healthy, Working Adults
Publication
NEJM
Publication Date
1995
Authors
Nichol K, Lind A, Karen K, Murdoch M, et al.
Volume & Issue
Volume 333, Issue 14
Pages
889-93
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Immunization significantly lowers rates of leading infectious diseases
    Impact of Immunization on the Number of Annual Cases of Disease in the USA  
  • Staff vaccination in nursing homes reduces mortality rates of residents
    Mortality rates in nursing home residents were 42% lower in facilities with higher staff vaccination coverage compared with control facilities.  
  • Pre-surgery antibiotic use reduces 6-day mortality by 50% in elderly
    Effective pre-surgery antibiotic use can reduce 60-day mortality in the elderly by 50%.  
  • Savings from flu vaccine
    Vaccination for influenza resulted in an average annual cost savings of $13.66 per healthy working adult vaccinated.  
  • Vaccines cost ~$50 per healthy life year saved
    Most vaccinations cost less than $50 per healthy life year saved. In contrast, treating hypertension costs between $4,340 and $87,940 per healthy life year saved.