Silver Book Fact

Use of stem cells to create neurons could enable the study of the response of human cells to new drugs in vitro, early in the drug development process.

Woolf, Clifford J. Overcoming Obstacles to Developing New Analgesics. Nature Med. 2010; 16(11): 1241-7. http://www.nature.com/nm/journal/v16/n11/full/nm.2230.html

Reference

Title
Overcoming Obstacles to Developing New Analgesics
Publication
Nature Med
Publication Date
2010
Authors
Woolf, Clifford J
Volume & Issue
Volume 16, Issue 11
Pages
1241-7
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Subthalamic nuclei deep brain stimulation (STN-DBS) raises pain thresholds in Parkinson’s disease patients.  
  • Brain imaging is showing that pain changes the structure and function of brain regions that perceive pain, making it persistent. These brain networks and receptor targets are being identified…  
  • The combination of information for neuroimaging and circulatory biomarkers could improve both the sensitivity and specificity of pain diagnosis and thereby improve treatment.  
  • An oral cannabinoid was found effective in relieving diabetic peripheral neuropathic pain symptoms and improving disturbed sleep, quality of life, and overall patient status.  
  • Topical capsaicin was found in a meta-analysis to provide a degree of pain relief to some patients with painful neuropathic conditions.