Silver Book Fact

Use of ACE inhibitor drugs for people with congestive heart failure helped avoid $9,000 per person in hospital costs over a 3-year period and reduced deaths by 16%.

The SOLVD Investigators. Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure. N Engl J Med. 1991; 325(5): 293-302. http://content.nejm.org/cgi/content/abstract/325/5/293

Reference

Title
Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure
Publication
N Engl J Med
Publication Date
1991
Authors
The SOLVD Investigators
Volume & Issue
Volume 325, Issue 5
Pages
293-302
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Economic Value

Related Facts

  • Aspirin, beta-blockers, angiotensin-converting enzyme inhibitors, and statins, when taken in combination, have been estimated to reduce the relative risk of coronary heart disease mortality by 80%, compared with a placebo.  
  • Assuming that Medicare Part D covers about 37% of beneficiaries’ drug costs, it is estimated that providing post-myocardial infarction Medicare beneficiaries with full coverage for combination pharmcotherapy will save more…  
  • The age-adjusted stroke mortality rate has decreased 70% since 1950, and 64% since 1972.  
  • TAVR v. SAVR in Intermediate-Risk SAS Patients
    At 1-year, severe aortic stenosis (SAS) patients with intermediate surgical mortality risk who underwent transcatheter aortic valve replacement (TAVR), had all-cause mortality rates of 7.4% (compared to 13% for surgical…  
  • It is estimated that the number of quality-adjusted life-years achieved with each $1 million spent on antihypertensive drug therapy is between 20-50 to more than 200.