Silver Book Fact

Understanding the role of genetics in pain mechanisms is increasing and the potential now exists to conduct genome-wide screens in model organisms to look for pain-associated genes.

Institute of Medicine; Committee on Advancing Pain Research, Care and Education. Relieving Pain in America: A blueprint for transforming prevention, care, education, and research. Washington, DC: National Academies Press; 2011. http://www.iom.edu/Reports/2011/Relieving-Pain-in-America-A-Blueprint-for-Transforming-Prevention-Care-Education-Research.aspx

Reference

Title
Relieving Pain in America: A blueprint for transforming prevention, care, education, and research
Publisher
National Academies Press
Publication Date
2011
Authors
Institute of Medicine; Committee on Advancing Pain Research, Care and Education
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Resolvins, a family of lipid mediators, have shown potential in resolving persistent inflammatory pain.  
  • Topical capsaicin was found in a meta-analysis to provide a degree of pain relief to some patients with painful neuropathic conditions.  
  • Targeting A-type K+ channels in primary sensory neurons could provide a novel mechanism-based therapy for the treatment of bone cancer pain–one of the most severe types of chronic pain.  
  • Topical NSAIDs were found in a meta-analysis to be significantly more effective than placebo in reducing persistent pain from musculoskeletal conditions.  
  • Pain education programs and pain consultations have been found to improve pain (average pain was 31% versus 20%) and daily interference (20% versus 2.5%) in oncology outpatients. Patient adherence…