Silver Book Fact
New antibacterial agents between 1983 and 2012

Total number of new antibacterial agents is in decline
Spellberg B, Guidos R, Gilbert D, Bradley J, et al. The Epidemic of Antibiotic-Resistant Infections: A call to action for the medical community from the Infectious Diseases Society of America. Clin Infect Dis. 2008; 46(2): 155-64. http://cid.oxfordjournals.org/content/46/2/155.full