Silver Book

Silver Book Fact

New antibacterial agents between 1983 and 2012

Fact image

Total number of new antibacterial agents is in decline

Spellberg B, Guidos R, Gilbert D, Bradley J, et al. The Epidemic of Antibiotic-Resistant Infections: A call to action for the medical community from the Infectious Diseases Society of America. Clin Infect Dis. 2008; 46(2): 155-64. http://cid.oxfordjournals.org/content/46/2/155.full

Reference

Title
The Epidemic of Antibiotic-Resistant Infections: A call to action for the medical community from the Infectious Diseases Society of America
Publication
Clin Infect Dis
Publication Date
2008
Authors
Spellberg B, Guidos R, Gilbert D, Bradley J, et al
Volume & Issue
Volume 46, Issue 2
Pages
155-64
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Publications

Healthcare-Associated Infections Factsheet

 https://www.silverbook.org/wp-content/uploads/2015/06/Screen-Shot-2015-06-30-at-3.02.28-PM.png Thumbnail

Related Facts

  • Infection control program reduced hospital-acquired HAIs by > 1/3
    A multimodal infection control program reduced the rate of hospital-acquired HAIs by more than 1/3 and improved quality of care and patient outcomes.  
  • Pre-surgery antibiotic use reduces 6-day mortality by 50% in elderly
    Effective pre-surgery antibiotic use can reduce 60-day mortality in the elderly by 50%.  
  • Over 8 years infection control practices saved ~27,000 lives and $1.8 billion
    Infection control practices saved an estimated 27,000 lives and $1.8 billion in medical costs between 2001 and 2009.  
  • Negative value of antibiotics to drug companies
    The value of an antibiotic to a drug company is negative $50 million- compared to the positive value of $1 billion for a new musculoskeletal drug.  
  • An antibiotic stewardship program saved $17 million over 8 years
    An antibiotic stewardship program saved a total of $17 million over 8 years, with antibiotic costs rising $1 million in the first year after discontinuation.