Silver Book Fact

Topical NSAIDs were found in a meta-analysis to be significantly more effective than placebo in reducing persistent pain from musculoskeletal conditions.

Derry, Sheena, R Andrew Moore, and Roy Rabbie. Topical NSAIDs for Chronic Musculoskeletal Pain in Adults. Cochrane Database of Systemic Reviews. 2012; http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007400.pub2/abstract;jsessionid=59B047BE4B4F53FCE12F2A8B0DFFF782.d03t02?deniedAccessCustomisedMessage=&userIsAuthenticated=false

Reference

Title
Topical NSAIDs for Chronic Musculoskeletal Pain in Adults
Publication
Cochrane Database of Systemic Reviews
Publication Date
2012
Authors
Derry, Sheena, R Andrew Moore, and Roy Rabbie
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • The use of sodium oxybate (SXB) in fibromylagia patients reduced pain by 30% or more in 54-58% of patients (versus 35.2% for placebo). SXB also reduced fatigue and sleep disturbance.  
  • Opioids have been found to reduce pain intensity and improve physical functioning for patients with persistent noncancer pain. It’s important to note that a decrease in mental health functioning…  
  • A biopsychosocial approach (i.e., one that takes into account physical, emotional, and environmental factors in the assessment and treatment of pain) has been found to improve the pain care of…  
  • Targeting A-type K+ channels in primary sensory neurons could provide a novel mechanism-based therapy for the treatment of bone cancer pain–one of the most severe types of chronic pain.  
  • People with persistent pain who used complementary and alternative medicine (CAM) had lower average health care expenditures than nonusers ($3,797 versus $4,153).