Silver Book Fact

Topical capsaicin was found in a meta-analysis to provide a degree of pain relief to some patients with painful neuropathic conditions.

Derry S, Lloyd R, Moore R, McQuay H. Topical Capsaicin for Chronic Neuropathic Pain in Adults. Cochrane Database of Systematic Reviews. 2009; 4. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007393.pub2/otherversions

Reference

Title
Topical Capsaicin for Chronic Neuropathic Pain in Adults
Publication
Cochrane Database of Systematic Reviews
Publication Date
2009
Authors
Derry S, Lloyd R, Moore R, McQuay H
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • The combination of information for neuroimaging and circulatory biomarkers could improve both the sensitivity and specificity of pain diagnosis and thereby improve treatment.  
  • A proteasome inhibitor was found to reduce pain and joint destruction in an animal model of osteoarthritis, suggesting that nontoxic proteasome inhibitors could offer a novel pharmacotherapy option.  
  • Exercise has shown to be effective in reducing persistent pain from osteoarthritis of the knee.  
  • Topical capsaicin was found in a meta-analysis to provide a degree of pain relief to some patients with painful neuropathic conditions.  
  • Targeting A-type K+ channels in primary sensory neurons could provide a novel mechanism-based therapy for the treatment of bone cancer pain–one of the most severe types of chronic pain.