Silver Book Fact

The use of ACE inhibitors in hypertensive patients 80 years of older was associated in this study with a 30% reduction in the rate of stroke and a 64% reduction in the rate of heart failure. Additionally, these patients had 39% fewer fatal strokes, a 23% lower rate of cardiovascular events, and 21% fewer deaths from all causes.

Beckett N, Peters R, Fletcher A, Staessen J, et al. Treatment of Hypertension in Patients 80 Years of Age or Older. NEJM. 2008; 358(18): 1887-98. http://content.nejm.org/cgi/content/short/NEJMoa0801369

Reference

Title
Treatment of Hypertension in Patients 80 Years of Age or Older
Publication
NEJM
Publication Date
2008
Authors
Beckett N, Peters R, Fletcher A, Staessen J, et al
Volume & Issue
Volume 358, Issue 18
Pages
1887-98
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Atrial fibrillation ablation prevents recurrence of AFib
    Atrial fibrillation ablation, which involves using a catheter inserted into the heart to destroy electrical conduction tissue in or near the atria, prevents the recurrence of atrial fibrillation in up…  
  • Primary angioplasty reduces 30-day mortality risk by 34% to 50%.  
  • A study looking at the effects of cardiovascular medicines in elderly patients who had previous heart attacks, found a total death rate reduction of 24% between 1995 and 2004.  
  • t-PA cost savings
    The total annual benefit to society from t-PA use in the United States is around $363 million—$60 million in direct cost savings to society plus an additional 7,510 QALYs. This means…  
  • The projected economic value of eliminating deaths from stroke is $7.6 trillion.