The projected total cost of ischemic stroke from 2005 to 2050 (in 2005 dollars) is around $2.2 trillion.
Brown, DL, B Boden-Albala, KM Langa, LD Lisabeth, M Fair, MA Smith, RL Sacco, and LB Morgenstern. Projected Costs of Ischemic Stroke in the United States. Neurology. 2006; 67(8): 1390-5. http://www.neurology.org/content/67/8/1390.abstract