Silver Book Fact
The estimated annual cost of persistent pain of $560 to $635 billion includes health care costs ($261 to $300 billion) and lost productivity ($299 to $335 billion). However, these estimates are conservative because they do not include the cost of pain for institutionalized individuals, military personnel, children, and personal caregivers. They also do not include the emotional costs of persistent pain or the lost productivity of workers younger than 24 or older than 65.
Gaskin D, Richard P. The Economic Costs of Pain in the United States. J Pain. 2012; 13(8): 715-24. http://www.jpain.org/article/S1526-5900(12)00559-7/abstract