Silver Book Fact

The combination of information for neuroimaging and circulatory biomarkers could improve both the sensitivity and specificity of pain diagnosis and thereby improve treatment.

Woolf C. Overcoming Obstacles to Developing New Analgesics. Nature Med. 2010; 16(11): 1241-7. http://www.nature.com/nm/journal/v16/n11/full/nm.2230.html

Reference

Title
Overcoming Obstacles to Developing New Analgesics
Publication
Nature Med
Publication Date
2010
Authors
Woolf C
Volume & Issue
Volume 16, Issue 11
Pages
1241-7
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Use of stem cells to create neurons could enable the study of the response of human cells to new drugs in vitro, early in the drug development process.  
  • Understanding the role of genetics in pain mechanisms is increasing and the potential now exists to conduct genome-wide screens in model organisms to look for pain-associated genes.  
  • Researchers have discovered that some types of glial cells have a major impact on persistent neuropathic pain and that targeting these cells may result in a new class of disease…  
  • Researchers have developed several sub-types of ion channels that allow inflammation and growth factors to trigger persistent pain.  
  • Statin use in mouse models show pain-alleviating effects for neuropathic pain.