Silver Book Fact

Targeting A-type K+ channels in primary sensory neurons could provide a novel mechanism-based therapy for the treatment of bone cancer pain–one of the most severe types of chronic pain.

Duan K, Xu Q, Zhang X, Zhao Z, et al. Targeting A-Type K+ Channels in Primary Sensory Neurons for Bone Cancer Pain in a Rat Model. Pain. 2012; 153(3): 562-74. http://www.ncbi.nlm.nih.gov/pubmed/22188869

Reference

Title
Targeting A-Type K+ Channels in Primary Sensory Neurons for Bone Cancer Pain in a Rat Model
Publication
Pain
Publication Date
2012
Authors
Duan K, Xu Q, Zhang X, Zhao Z, et al.
Volume & Issue
Volume 153, Issue 3
Pages
562-74
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Topical capsaicin was found in a meta-analysis to provide a degree of pain relief to some patients with painful neuropathic conditions.  
  • The Mayo Clinic Pain Rehabilitation Center helps people with persistent pain return to an active lifestyle and has found that among patients who finish the program, nearly 84% report greater…  
  • Understanding the role of genetics in pain mechanisms is increasing and the potential now exists to conduct genome-wide screens in model organisms to look for pain-associated genes.  
  • 60% of people with persistent back pain who turned to complementary and alternative medicine perceived a “”great deal”” of benefit.  
  • Acupuncture, in combination with routine care, was associated with marked clinical improvements in patients with persistent low back pain. It has also shown improvement in primary and secondary outcomes…