Silver Book Fact

Statin use in mouse models show pain-alleviating effects for neuropathic pain.

Shi X, Lim T, Lee S, Zhao Y, et al. Statins Alleviate Experimental Nerve-Injury Induced Neuropathic Pain. Pain. 2011; 152(5): 1033-43. https://insights.ovid.com/pubmed?pmid=21414721

Reference

Title
Statins Alleviate Experimental Nerve-Injury Induced Neuropathic Pain
Publication
Pain
Publication Date
2011
Authors
Shi X, Lim T, Lee S, Zhao Y, et al
Volume & Issue
Volume 152, Issue 5
Pages
1033-43
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Pain education programs and pain consultations have been found to improve pain (average pain was 31% versus 20%) and daily interference (20% versus 2.5%) in oncology outpatients. Patient adherence…  
  • Advances in neuroimaging will continue to offer information on the brain’s functioning and how it correlates to the pain experience.  
  • Antiepileptic drugs relieve persistent neuropathic pain. One meta-analysis found gabapentin to be associated with moderate benefit (equivalent to 30% pain relief) in close to 1 in 2 patients, and…  
  • A proteasome inhibitor was found to reduce pain and joint destruction in an animal model of osteoarthritis, suggesting that nontoxic proteasome inhibitors could offer a novel pharmacotherapy option.  
  • Statin use in mouse models show pain-alleviating effects for neuropathic pain.