Silver Book Fact

Researchers have discovered that some types of glial cells have a major impact on persistent neuropathic pain and that targeting these cells may result in a new class of disease modifying therapies.

Institute of Medicine; Committee on Advancing Pain Research, Care and Education. Relieving Pain in America: A blueprint for transforming prevention, care, education, and research. Washington, DC: National Academies Press; 2011. http://www.iom.edu/Reports/2011/Relieving-Pain-in-America-A-Blueprint-for-Transforming-Prevention-Care-Education-Research.aspx

Reference

Title
Relieving Pain in America: A blueprint for transforming prevention, care, education, and research
Publisher
National Academies Press
Publication Date
2011
Authors
Institute of Medicine; Committee on Advancing Pain Research, Care and Education
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Targeting A-type K+ channels in primary sensory neurons could provide a novel mechanism-based therapy for the treatment of bone cancer pain–one of the most severe types of chronic pain.  
  • Subthalamic nuclei deep brain stimulation (STN-DBS) raises pain thresholds in Parkinson’s disease patients.  
  • People with persistent pain who used complementary and alternative medicine (CAM) had lower average health care expenditures than nonusers ($3,797 versus $4,153).  
  • Resolvins, a family of lipid mediators, have shown potential in resolving persistent inflammatory pain.  
  • A meta-analysis of pscychological interventions for chronic low back pain found small but statistically significant effects for all interventions for as long as 5 years.