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Survival rates of sSAS patients who do not undergo valve replacement

Patients with severe symptomatic aortic stenosis (sSAS) who do not undergo valve replacement have survival rates as low as 50% at two years and 20% at 5 years after the onset of symptoms.

Otto C. Timing of Aortic Valve Surgery. Heart. 2000; 84. http://heart.bmj.com/content/84/2/211

Reference

Title
Timing of Aortic Valve Surgery
Publication
Heart
Publication Date
2000
Authors
Otto C
URL
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Categories

  • Cost of Disease
  • Human Burden

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Aortic Stenosis Fact Sheet

 https://www.silverbook.org/wp-content/uploads/2017/10/AS-FS-cover.png Thumbnail

Connected Facts

Aortic Stenosis

2016 prevalence of aortic valve disease in America

In 2016, as many as 5.8 million U.S. adults had aortic valve disease (AVD).

Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence
estimates by Bach et al. 2007

Prevalence & Incidence

Aortic Stenosis

Survival Rates Over 5 Years for Patients with Medically Managed Severe Aortic Stenosis

Human Burden

Aortic Stenosis

Increased hospital admissions and prolonged length of stay for patients who do not undergo treatment

Medicare severe symptomatic aortic stenosis (sSAS) patients who do not undergo treatment have an average of 1.9 hospital admissions per year and prolonged lengths of stay — 11.5 hospital days per patient-year.

Human Burden

Aortic Stenosis

All-cause mortality for aortic valve disorders

In 2014, all-cause mortality for aortic valve disorders was 34,408 in the U.S.

Human Burden

Aortic Stenosis

1 and 6-month mortality rates without treatment for sSAS

Waiting for treatment for severe symptomatic aortic stenosis (sSAS) can be deadly, with 1-month mortality at 3.7% and 6-month mortality at 11.6% (measured from the time intervention was recommended).

Human Burden

Aortic Stenosis

Lifespan of Medicare patients with sSAS who do not undergo treatment

Medicare patients with severe symptomatic aortic stenosis (sSAS) who do not undergo treatment have an average lifespan of 1.8 years.

Human Burden

Related Facts

  • Aortic valve disease costs
    Aortic valve disease (AVD) (symptomatic and asymptomatic) costs the U.S. $10.2 billion in direct costs each year.  
  • 2016 prevalence of aortic valve disease in America
    In 2016, as many as 5.8 million U.S. adults had aortic valve disease (AVD). Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence estimates by Bach et al. 2007  
  • Low detection rates for AS
    Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.  
  • Prevalence of AS in Americans 75+
    An estimated 12.4%, or ~2.5 million people ages 75+ in North America, have AS.  
  • Mean 5-Year Cumulative Total Medical Costs Per Medically Managed (No AVR) Severe AS Patient