Silver Book Fact

Nerve growth factor (NGF) has been found to be a major mediator of inflammatory and neuropathic pain and provides a new therapeutic target.

Watson J, Allen S, Dawbarn D. Targeting New Growth Factor in Pain: What is the therapeutic potential?. BioDrugs. 2008; 22(6): 349-59. http://www.mendeley.com/catalog/targeting-nerve-growth-factor-pain-therapeutic-potential/

Reference

Title
Targeting New Growth Factor in Pain: What is the therapeutic potential?
Publication
BioDrugs
Publication Date
2008
Authors
Watson J, Allen S, Dawbarn D
Volume & Issue
Volume 22, Issue 6
Pages
349-59
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Topical NSAIDs were found in a meta-analysis to be significantly more effective than placebo in reducing persistent pain from musculoskeletal conditions.  
  • An oral cannabinoid was found effective in relieving diabetic peripheral neuropathic pain symptoms and improving disturbed sleep, quality of life, and overall patient status.  
  • 60% of people with persistent back pain who turned to complementary and alternative medicine perceived a “”great deal”” of benefit.  
  • Targeting A-type K+ channels in primary sensory neurons could provide a novel mechanism-based therapy for the treatment of bone cancer pain–one of the most severe types of chronic pain.  
  • Pain education programs and pain consultations have been found to improve pain (average pain was 31% versus 20%) and daily interference (20% versus 2.5%) in oncology outpatients. Patient adherence…