Connected Facts

Mitral Valve Disease

Mitral valve disease is present in 5.1% of the population ages 65 and older.

Age - A Major Risk Factor

Valve Disease

Risk of heart valve disease increases with age

Between the ages of 18 and 44, less than 1% of the U.S. population has heart valve disease. This increases to 8.5% between ages 65 and 74, and 13.2% after age 75.

Age - A Major Risk Factor, Human Burden

Valve Disease

Prevalence estimates for heart valve disease are likely low.

A U.K. population screening found previously undetected heart valve disease in 1 in 2 adults ages 65+.

Aortic Stenosis

Aortic stenosis often undertreated

Cost of Disease

Related Facts

• 2016 prevalence of aortic valve disease in America

  In 2016, as many as 5.8 million U.S. adults had aortic valve disease (AVD). Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence estimates by Bach et al. 2007  [ Get More Details ]
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  Aortic stenosis often undertreated

   [ Get More Details ]

• Projections of Significant Heart Valve Disease — Diagnosed & Undiagnosed — in the 65+ U.K. Population

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• 1 and 6-month mortality rates without treatment for sSAS

  Waiting for treatment for severe symptomatic aortic stenosis (sSAS) can be deadly, with 1-month mortality at 3.7% and 6-month mortality at 11.6% (measured from the time intervention was recommended).  [ Get More Details ]

• Survival rates of sSAS patients who do not undergo valve replacement

  Patients with severe symptomatic aortic stenosis (sSAS) who do not undergo valve replacement have survival rates as low as 50% at two years and 20% at 5 years after the…  [ Get More Details ]