Connected Facts

Mitral Valve Disease

Mitral valve disease is present in 5.1% of the population ages 65 and older.

Age - A Major Risk Factor

Valve Disease

Risk of heart valve disease increases with age

Between the ages of 18 and 44, less than 1% of the U.S. population has heart valve disease. This increases to 8.5% between ages 65 and 74, and 13.2% after age 75.

Age - A Major Risk Factor, Human Burden

Valve Disease

Prevalence estimates for heart valve disease are likely low.

A U.K. population screening found previously undetected heart valve disease in 1 in 2 adults ages 65+.

Aortic Stenosis

Aortic stenosis often undertreated

Cost of Disease

Related Facts

• Lifespan of Medicare patients with sSAS who do not undergo treatment

  Medicare patients with severe symptomatic aortic stenosis (sSAS) who do not undergo treatment have an average lifespan of 1.8 years.  [ Get More Details ]

• 2016 prevalence of Americans 65+ who had AVD

  In 2016, an estimated 5.2 million U.S. adults ages 65+ had aortic valve disease (AVD).   Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence estimates by Bach et al. 2007  [ Get More Details ]

• 1 and 6-month mortality rates without treatment for sSAS

  Waiting for treatment for severe symptomatic aortic stenosis (sSAS) can be deadly, with 1-month mortality at 3.7% and 6-month mortality at 11.6% (measured from the time intervention was recommended).  [ Get More Details ]

• Mean 5-Year Cumulative Total Medical Costs Per Medically Managed (No AVR) Severe AS Patient

   [ Get More Details ]

• Low detection rates for AS

  Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.  [ Get More Details ]