Connected Facts

Mitral Valve Disease

Mitral valve disease is present in 5.1% of the population ages 65 and older.

Age - A Major Risk Factor

Valve Disease

Risk of heart valve disease increases with age

Between the ages of 18 and 44, less than 1% of the U.S. population has heart valve disease. This increases to 8.5% between ages 65 and 74, and 13.2% after age 75.

Age - A Major Risk Factor, Human Burden

Valve Disease

Prevalence estimates for heart valve disease are likely low.

A U.K. population screening found previously undetected heart valve disease in 1 in 2 adults ages 65+.

Aortic Stenosis

Aortic stenosis often undertreated

Cost of Disease

Related Facts

• 1 and 6-month mortality rates without treatment for sSAS

  Waiting for treatment for severe symptomatic aortic stenosis (sSAS) can be deadly, with 1-month mortality at 3.7% and 6-month mortality at 11.6% (measured from the time intervention was recommended).  [ Get More Details ]

• Survival Rates Over 5 Years for Patients with Medically Managed Severe Aortic Stenosis

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• Aortic valve disease costs

  Aortic valve disease (AVD) (symptomatic and asymptomatic) costs the U.S. $10.2 billion in direct costs each year.  [ Get More Details ]

• Low detection rates for AS

  Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.  [ Get More Details ]

• Mean 5-Year Cumulative Total Medical Costs Per Medically Managed (No AVR) Severe AS Patient

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