Connected Facts

Mitral Valve Disease

Mitral valve disease is present in 5.1% of the population ages 65 and older.

Age - A Major Risk Factor

Valve Disease

Risk of heart valve disease increases with age

Between the ages of 18 and 44, less than 1% of the U.S. population has heart valve disease. This increases to 8.5% between ages 65 and 74, and 13.2% after age 75.

Age - A Major Risk Factor, Human Burden

Valve Disease

Prevalence estimates for heart valve disease are likely low.

A U.K. population screening found previously undetected heart valve disease in 1 in 2 adults ages 65+.

Aortic Stenosis

Aortic stenosis often undertreated

Cost of Disease

Related Facts

• Undertreatment of patients with sSAS

  AS is often undertreated — one study found that 56% of severe symptomatic aortic stenosis (sSAS) patients referred to a cardiothoracic surgeon were not operated on.  [ Get More Details ]

• Increased hospital admissions and prolonged length of stay for patients who do not undergo treatment

  Medicare severe symptomatic aortic stenosis (sSAS) patients who do not undergo treatment have an average of 1.9 hospital admissions per year and prolonged lengths of stay — 11.5 hospital days…  [ Get More Details ]

• Mean 5-Year Cumulative Total Medical Costs Per Medically Managed (No AVR) Severe AS Patient

   [ Get More Details ]

• Projections of Significant Heart Valve Disease — Diagnosed & Undiagnosed — in the 65+ U.K. Population

   [ Get More Details ]

• Low detection rates for AS

  Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.  [ Get More Details ]