Connected Facts

Mitral Valve Disease

Mitral valve disease is present in 5.1% of the population ages 65 and older.

Age - A Major Risk Factor

Valve Disease

Risk of heart valve disease increases with age

Between the ages of 18 and 44, less than 1% of the U.S. population has heart valve disease. This increases to 8.5% between ages 65 and 74, and 13.2% after age 75.

Age - A Major Risk Factor, Human Burden

Valve Disease

Prevalence estimates for heart valve disease are likely low.

A U.K. population screening found previously undetected heart valve disease in 1 in 2 adults ages 65+.

Aortic Stenosis

Aortic stenosis often undertreated

Cost of Disease

Related Facts

• 1 and 6-month mortality rates without treatment for sSAS

  Waiting for treatment for severe symptomatic aortic stenosis (sSAS) can be deadly, with 1-month mortality at 3.7% and 6-month mortality at 11.6% (measured from the time intervention was recommended).  [ Get More Details ]

• Prevalence of AS in Americans 75+

  An estimated 12.4%, or ~2.5 million people ages 75+ in North America, have AS.  [ Get More Details ]
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  Survival rates for patients with sSAS without repair or replacement

   [ Get More Details ]
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  Survival rates for SAS patients without treatment

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• Aortic valve disease costs

  Aortic valve disease (AVD) (symptomatic and asymptomatic) costs the U.S. $10.2 billion in direct costs each year.  [ Get More Details ]