Silver Book Fact

Adjusted-dose warfarin reduced stroke risk in AFib patients

Meta-analysis of randomized trials found that adjusted-dose warfarin reduced stroke risk in atrial fibrillation
patients by 60%. Antiplatelet agents reduced risk by 20%.

Hart R, Pearce L, Aguilar M. Meta-Analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med. 2007; 146(12): 857-67. http://www.annals.org/content/146/12/857.full

Reference

Title
Meta-Analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation
Publication
Ann Intern Med
Publication Date
2007
Authors
Hart R, Pearce L, Aguilar M
Volume & Issue
Volume 146, Issue 12
Pages
857-67
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Decrease in AFib hospitalization rates
    The use of practice guidelines in atrial fibrillation patients saw a decrease in rate of hospitalization from 74%to 38%.  
  • Atrial fibrillation ablation prevents recurrence of AFib
    Atrial fibrillation ablation, which involves using a catheter inserted into the heart to destroy electrical conduction tissue in or near the atria, prevents the recurrence of atrial fibrillation in up…  
  • Cost-savings associated with optimal anticoagulation in AFib patients
    If half of all atrial fibrillation patients receiving suboptimal or no anticoagulation instead received optimal anticoagulation, 28,000 strokes could be prevented each year at a savings of around $2.5 billion in direct…  
  • Per-patient annual cost of treating stroke in atrial fibrillation patients
    The per-patient annual cost of treating stroke in atrial fibrillation patients was found to be $1,485 in a wellcontrolled anti-coagulation clinic, $3,710 for those receiving warfarin in routine medical care,…  
  • Adjusted-dose warfarin reduced stroke risk in AFib patients
    Meta-analysis of randomized trials found that adjusted-dose warfarin reduced stroke risk in atrial fibrillation patients by 60%. Antiplatelet agents reduced risk by 20%.