Silver Book Fact
Adjusted-dose warfarin reduced stroke risk in AFib patients
Meta-analysis of randomized trials found that adjusted-dose warfarin reduced stroke risk in atrial fibrillation
patients by 60%. Antiplatelet agents reduced risk by 20%.
Hart R, Pearce L, Aguilar M. Meta-Analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med. 2007; 146(12): 857-67. http://www.annals.org/content/146/12/857.full