Silver Book

Silver Book Fact

Aspirin use in AFib patients

Meta-analysis of a number of randomized controlled trials found that aspirin use in atrial fibrillation patients
reduced stroke risk by an average 22%.

Hart, RG, O Benavente, R McBride, and LA Pearce. Antithrombotic Therapy to Prevent Stroke in Patients with Atrial Fibrillation. Ann Intern Med. 1999; 131(7): 492-501. http://www.annals.org/content/131/7/492.1.full

Reference

Title
Antithrombotic Therapy to Prevent Stroke in Patients with Atrial Fibrillation
Publication
Ann Intern Med
Publication Date
1999
Authors
Hart, RG, O Benavente, R McBride, and LA Pearce
Volume & Issue
Volume 131, Issue 7
Pages
492-501
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Adjusted-dose warfarin reduced stroke risk in AFib patients
    Meta-analysis of randomized trials found that adjusted-dose warfarin reduced stroke risk in atrial fibrillation patients by 60%. Antiplatelet agents reduced risk by 20%.  
  • Stroke prevention through optimal anticoagulation
    If half of atrial fibrillation patients who currently receive warfarin in a routine care setting had their anti-coagulation optimized, around 9,000 strokes and more than 29,000 bleeds would be prevented.  
  • Stroke risk reduction from thrombin inhibitor in AFib patients
    A recently approved direct thrombin inhibitor was found to reduce the risk of stroke/peripheral embolic events in atrial fibrillation patients by 34%, and the risk of hemorrhagic stroke by 74%—compared…  
  • AFib practice guidelines reduce direct health care costs
    The use of practice guidelines in atrial fibrillation (AF) patients significantly decreased hospitalization and resource utilization—with an average decrease in 30-day total direct health care costs of around $1,400 per patient.  
  • Effect of optimal anticoagulation
    If 50% of atrial fibrillation patients who currently receive warfarin in routine medical care were optimally anticoagulated, 9,852 emboli would be prevented and $1.3 billion would be saved each year.