Silver Book Fact

Life expectancy and quality of life gains from AVR

A study of 4,617 patients who underwent aortic valve replacement (AVR) over a period of 20 years found significant gains in life expectancy and quality of life — 43,166 net life-years gained at a net value of $11.2 billion (~$14.2 billion in 2017 dollars).

Wu Y, Grunkmeier G, Starr A. The Value of Aortic Valve Replacement in Elderly Patients: An economic analysis. J Thorac Cardiovasc Surg. 2007; 133(3): 603-7.


The Value of Aortic Valve Replacement in Elderly Patients: An economic analysis
J Thorac Cardiovasc Surg
Publication Date
Wu Y, Grunkmeier G, Starr A
Volume & Issue
Volume 133, Issue 3
Read Full Resource


  • Innovative Medical Research
  • Economic Value

Related Facts

  • From approval in 2011 through 2015 >54,000 TAVRs were performed in 418 centers in 48 states
  • Disease specific status and generic health status improvements from TAVR and SAVR
    Transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in intermediate risk symptomatic aortic stenosis (SAS) patients were associated with significant improvements in disease specific status (16 to…  
  • TAVR improves quality of life in SAS patients
  • TAVR Success in sSAS Patients
    A study of severe symptomatic aortic stenosis (sSAS) patients who received transcatheter aortic valve replacement (TAVR) found 30-day mortality of 2.2% for those who were high risk of surgical mortality/inoperable,…  
  • Surgical Aortic Valve Replacements in 2010
    In 2010, ~67,500 surgical aortic valve replacements (SAVR) were performed in the U.S.