Silver Book Fact

Infection and related sepsis leading cause of death in noncardiac-ICUs

Infection and related sepsis/septicemia are the leading cause of death in noncardiac-ICUs, accounting for as many as 60% of deaths.

Vincent, Jean-Louis, Jordi Rello, John Marshall, Eliezer Silva, Antonio Anzueto, Claude D. Martin, Rui Moreno, Jeffrey Lipman, Charles Gomersall, Yasser Sakr, Konrad Reinhart. International Study of the Prevalence and Outcomes of Infection in Intensive Care Units. JAMA. 2009; 302(21): 2323-9. http://jama.jamanetwork.com/article.aspx?articleid=184963

Reference

Title
International Study of the Prevalence and Outcomes of Infection in Intensive Care Units
Publication
JAMA
Publication Date
2009
Authors
Vincent, Jean-Louis, Jordi Rello, John Marshall, Eliezer Silva, Antonio Anzueto, Claude D. Martin, Rui Moreno, Jeffrey Lipman, Charles Gomersall, Yasser Sakr, Konrad Reinhart
Volume & Issue
Volume 302, Issue 21
Pages
2323-9
URL
Read Full Resource

Categories

  • Cost of Disease
  • Human Burden

Related Facts

  • Drug-resistant MRSA expensive to treat
    As an example, the median treatment cost for drug-resistant MRSA patients over a 6-month period was 118% higher than the cost of treating drug-susceptible MRSA strains.  
  • Sepsis accounts for 17% of in-hospital deaths
    In 2008, only 2% of hospitalization were for sepsis/septicemia, yet they made up 17% of in-hospital deaths.  
  • ~1 in 20 hospitalized patients will get an HAI
    Around 1 in 20 hospitalized patients will contract a healthcare-associated infection, the most common complication of hospital care.  
  • Antibiotic resistance of Klebsiella pneumoniae on the rise
    Resistance of Klebsiella pneumoniae to antibiotics has dramatically increased- from 5.3% to 11.6% for third generation cephalosporins (between 1999 and 2010), and from <0.1% to 4.5% for carbapenams (between 2002…  
  • Hospital stays longer when HAIs involved
    The average length of hospital stays are 19 days longer with healthcare-associated infections than without (24.4 days versus 5.2 days).