Silver Book Fact
Dramatic increase of antibiotic resistance between 1981 and 2001

Increase in antibiotic resistance over 20 year period
National Nosocomial Infections Surveillance (NNIS) System. National Nosocomial Infections Surveillance (NNIS) System Report, Data Summary from January 1990 – May 1999, Issued June 1999. Am J Infect Control. 1999; 27(6): 520-32. http://www.ajicjournal.org/article/S0196-6553%2899%2970031-3/fulltext