Silver Book Fact

Fact image

In a trial with 160 participants who had type 2 diabetes, intensive intervention with multiple drug combinations and behavior modification benefited patients with respect to vascular complications and on rates of death from any cause and cardiovascular causes. One example, shown in the graph below, shows the progression of diabetic retinopathy in the two groups at 4, 8, and 13 year intervals.

Gaede P, Lund-Andersen H, Parving H, Pedersen O. Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes. NEJM. 2008; 358(6): 580-91. https://www.nejm.org/doi/full/10.1056/nejmoa0706245

Reference

Title
Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes
Publication
NEJM
Publication Date
2008
Authors
Gaede P, Lund-Andersen H, Parving H, Pedersen O
Volume & Issue
Volume 358, Issue 6
Pages
580-91
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Blood pressure control in diabetics reduces the risk of cardiovascular disease by 33% to 50%, and the risk of microvascular complications by approximately 33%.  
  • Blood pressure control reduces the risk of heart disease or stroke among Americans with diabetes by 33-50%.  
  • Following the current path, diabetes cases will increase by 52.9% between 2003 and 2023. If an alternative path is taken, there will be 13.3% (2.8 million) fewer diabetes cases.  
  • To date, multiple genomewide comparisons of thousands of subjects with type 2 diabetes and controls without the disease have identified approximately twenty-five DNA variants that are significantly associated with type…  
  • Losing about 4 percent of your weight and keeping it off for the rest of your life could reduce your risk for a serious complication from diabetes or from dying…