Silver Book Fact

Fact image

In a trial with 160 participants who had type 2 diabetes, intensive intervention with multiple drug combinations and behavior modification benefited patients with respect to vascular complications and on rates of death from any cause and cardiovascular causes. One example, shown in the graph below, shows the progression of diabetic retinopathy in the two groups at 4, 8, and 13 year intervals.

Gaede P, Lund-Andersen H, Parving H, Pedersen O. Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes. NEJM. 2008; 358(6): 580-91. https://www.nejm.org/doi/full/10.1056/nejmoa0706245

Reference

Title
Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes
Publication
NEJM
Publication Date
2008
Authors
Gaede P, Lund-Andersen H, Parving H, Pedersen O
Volume & Issue
Volume 358, Issue 6
Pages
580-91
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Economics of DR Treatment
    Laser treatment plus a VEGF inhibitor achieved an incremental cost-effectiveness ratio of $12,410 per quality adjusted life year in patients with DME.  
  • Intensive Glycemic Control in People with Diabetes
    Intensive glycemic control in diabetics reduced their: Adjusted mean risk of DR by 76% Risk of progression by 54% Rates of laser surgery by 56% Risk of DME by 23%    
  • During the first year of a community pharmacy services program in 2003 which included 256 diabetes patients who used scheduled consultations, clinical goal setting, monitoring and collaborative drug therapy management…  
  • Treatment of diabetes with medication and other therapy saves $685-$950 in health care costs per patient within 1-2 years.  
  • The Diabetes Prevention Program showed that exercise and dietary changes targeting a 7 percent weight loss in participants with prediabetes reduced type 2 development by 58 percent over three years.