Silver Book Fact

Risk of HAIs from hospitalization increases with age

Fact image

Hospitalized elderly patients are 2 – 5 times more likely to develop a healthcare-associated infection than younger patients.

Haley R, Hooton T, Culver D, Stanley R, et al. Nosocomial Infections in U.S. Hospitals, 1975-1976. Am J Med. 1981; 70(4): 947-59.


Nosocomial Infections in U.S. Hospitals, 1975-1976
Am J Med
Publication Date
Haley R, Hooton T, Culver D, Stanley R, et al.
Volume & Issue
Volume 70, Issue 4
Read Full Resource


  • Cost of Disease
  • Age - A Major Risk Factor

Related Facts

  • 1 in 4 inpatient pneumonia hospitalizations due to HAIs
    In one study, one in four inpatient pneumonia hospitalizations were from health-care-associated pneumonia.  
  • Drug resistant infections cost $16.6 – $26 billion to US healthcare system annually
    Drug-resistant infections cost the U.S. healthcare system between $16.6 and $26 billion in extra costs each year.  
  • Late Mortality and Sepsis
    Compared with patients not in the hospital, sepsis in hospitalized patients was associated with a 22.1%  increase in late mortality during a 2 year follow-up period.  
  • HAIs cost patients additional $43,000 per hospital stay
    Patients with HAIs cost, on average, $43,000 more per hospital stay than those without an infection ($52,096 vs. $9,377).  
  • Hospital-acquired pneumonia leading cause of HAI
    Hospital-acquired pneumonia (HAP) is the 2nd most frequent cause of hospital-acquired infection, numbering around 300,000 cases each year.