Silver Book Fact

Postherpetic neuralgia in shingles

Fact image

Complications, including postherpetic neuralgia (PHN) occur in ~50% of older persons with shingles.

Oxman, M.N., M.J. Levin, G.R. Johnson, K.E. Schmader, S.E. Straus, et al; for the Shingles Prevention Study Group. A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults. NEJM. 2005; 352(22): 2271-84. http://www.nejm.org/doi/full/10.1056/NEJMoa051016

Reference

Title
A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults
Publication
NEJM
Publication Date
2005
Authors
Oxman, M.N., M.J. Levin, G.R. Johnson, K.E. Schmader, S.E. Straus, et al; for the Shingles Prevention Study Group
Volume & Issue
Volume 352, Issue 22
Pages
2271-84
URL
Read Full Resource

Categories

  • Cost of Disease
  • Human Burden

Related Facts

  • Death rate from pneumonia and flu rises significantly with age
    The death rate from pneumonia and influenza is close to 130 times higher in people age 85 and older, compared to people ages 45 to 54. This increased risk due…  
  • Healthcare use due to flu
    In the U.S. influenza epidemics lead to around: • 600,000 life years lost • 3 million hospitalized days • 30 million outpatient visits  
  • >1/2 of flu’s economic burden from people 65+
    An estimated 64% of the total economic burden of influenza comes from those over 65 years old.  
  • 1 in 20 age 85+ will have pneumonia
    Every year 1 in 20 Americans age 85+ will have an episode of community-acquired pneumonia.  
  • In 1998, community-acquired pneumonia was 6th leading cause of death
    Community-acquired pneumonia is the sixth leading cause of death in the U.S. and the number-one cause of death from infection.