Silver Book Fact

Postherpetic neuralgia in shingles

Fact image

Complications, including postherpetic neuralgia (PHN) occur in ~50% of older persons with shingles.

Oxman M, Levin M, Johnson G, Schmader K, et al. A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults. NEJM. 2005; 352(22): 2271-84. http://www.nejm.org/doi/full/10.1056/NEJMoa051016

Reference

Title
A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults
Publication
NEJM
Publication Date
2005
Authors
Oxman M, Levin M, Johnson G, Schmader K, et al.
Volume & Issue
Volume 352, Issue 22
Pages
2271-84
URL
Read Full Resource

Categories

  • Cost of Disease
  • Human Burden

Related Facts

  • Unplanned Hospital Readmissions & Costs Following Sepsis Hospitalizations
    Among 187,697 hospital admissions for medical reasons that were associated with an unplanned 30-day readmission,  147,084 had a diagnosis of sepsis, 15,001 had a diagnosis of AMI, 79,480 were diagnosed with heart failure, 54,396…  
  • Annual pneumonia, flu, and shingles cases
    Approximate annual number of new cases of leading infectious diseases in US: Pneumonia – 5 to 10 million Influenza – 35 to 50 million Herpes zoster (shingles) – 1 million  
  • Hospitalization rates in shingles patients rises with age
    Hospitalization rates for people with shingles are 75 times higher for people age 85+ than for those under the age of 30.  
  • Sepsis accounts for nearly 1/2 of ICU expenditures
    Infection and related sepsis/septicemia account for 40% of all ICU expenditures.  
  • 1 in 3 people will develop shingles
    An estimated 1 in 3 people will develop shingles in their lifetime.