Silver Book Fact

Postherpetic neuralgia in shingles

Fact image

Complications, including postherpetic neuralgia (PHN) occur in ~50% of older persons with shingles.

Oxman, M.N., M.J. Levin, G.R. Johnson, K.E. Schmader, S.E. Straus, et al; for the Shingles Prevention Study Group. A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults. NEJM. 2005; 352(22): 2271-84. http://www.nejm.org/doi/full/10.1056/NEJMoa051016

Reference

Title
A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults
Publication
NEJM
Publication Date
2005
Authors
Oxman, M.N., M.J. Levin, G.R. Johnson, K.E. Schmader, S.E. Straus, et al; for the Shingles Prevention Study Group
Volume & Issue
Volume 352, Issue 22
Pages
2271-84
URL
Read Full Resource

Categories

  • Cost of Disease
  • Human Burden

Related Facts

  • 1 in 4 inpatient pneumonia hospitalizations due to HAIs
    In one study, one in four inpatient pneumonia hospitalizations were from health-care-associated pneumonia.  
  • Infection and related sepsis leading cause of death in noncardiac-ICUs
    Infection and related sepsis/septicemia are the leading cause of death in noncardiac-ICUs, accounting for as many as 60% of deaths.  
  • Majority of C. diff deaths in ages 65+
    More than 90% of deaths from C. difficile infectious occur in people ages 65 and older.  
  • Drug resistant infections cost $16.6 – $26 billion to US healthcare system annually
    Drug-resistant infections cost the U.S. healthcare system between $16.6 and $26 billion in extra costs each year.  
  • Risk of HAIs from hospitalization increases with age
    Hospitalized elderly patients are 2 – 5 times more likely to develop a healthcare-associated infection than younger patients.