Silver Book Fact

~One-third of shingles death preventable with vaccine

Approximately one-third of shingles deaths may be preventable through vaccination.

Mahamud A, Marin M, Nickell S, Shoemaker T, et al. Herpes Zoster-Related Deaths in the United States: Validity of death certificates and mortality rates, 1979-2007. Clin Infect Dis. 2012; 55(7): 960-66. http://cid.oxfordjournals.org/content/55/7/960.full

Reference

Title
Herpes Zoster-Related Deaths in the United States: Validity of death certificates and mortality rates, 1979-2007
Publication
Clin Infect Dis
Publication Date
2012
Authors
Mahamud A, Marin M, Nickell S, Shoemaker T, et al.
Volume & Issue
Volume 55, Issue 7
Pages
960-66
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value
  • Future Value

Related Facts

  • Significant savings from zoster vaccine
    In a cost-effectiveness analysis, investigators estimated the zoster vaccine cost $44,000 per quality-adjusted life year saved for a 70-year-old woman.  
  • Effectiveness of pneumonia vaccine
    PPSV23 (pneumococcal polysaccharide vaccine) protects against 23 types of pneumococcal bacteria and is 60% to 80% effective in preventing pneumococcal bacteremia in adults over the age of 65 who are…  
  • Staff vaccination in nursing homes reduces mortality rates of residents
    Mortality rates in nursing home residents were 42% lower in facilities with higher staff vaccination coverage compared with control facilities.  
  • Use of shingles vaccines significantly reduced disease burden
    Use of a live attenuated VZV (varicella-zoster vaccine) in a randomized trial reduced the burden of illness from shingles by 61.1% and the incidence of postherpetic neuralgia (PHN) by 66.5%.  
  • Polio vaccination prevented 5 million cases of paralysis since 1988
    Vaccination for polio reduced the number of worldwide cases from more than 300,000 per year in the 1980s to only 2,000 in 2002—also preventing an estimated 5 million cases of…