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Aortic stenosis impacts majority of heart valve disease patients

Aortic stenosis (AS) is among the most common forms of heart valve disease (HVD), affecting 2% to 3% of the adult U.S. population.

Clark M, Arnold S, Duhay F, et al. Five-Year Clinical and Economic Outcomes Among Patients with Medically Managed Severe Aortic Stenosis: Results from a Medicare claims analysis. Circulation: Cardiovascular Quality and Outcomes. 2012; 5(5). http://circoutcomes.ahajournals.org/content/5/5/697

Reference

Title
Five-Year Clinical and Economic Outcomes Among Patients with Medically Managed Severe Aortic Stenosis: Results from a Medicare claims analysis.
Publication
Circulation: Cardiovascular Quality and Outcomes
Publication Date
2012
Authors
Clark M, Arnold S, Duhay F, et al
Volume & Issue
Volume 5, Issue 5
URL
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Categories

  • Prevalence & Incidence

Publications

Aortic Stenosis Fact Sheet

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Connected Facts

Aortic Stenosis

2016 prevalence of aortic valve disease in America

In 2016, as many as 5.8 million U.S. adults had aortic valve disease (AVD).

Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence
estimates by Bach et al. 2007

Prevalence & Incidence

Aortic Stenosis

1 and 6-month mortality rates without treatment for sSAS

Waiting for treatment for severe symptomatic aortic stenosis (sSAS) can be deadly, with 1-month mortality at 3.7% and 6-month mortality at 11.6% (measured from the time intervention was recommended).

Human Burden

Aortic Stenosis

Lifespan of Medicare patients with sSAS who do not undergo treatment

Medicare patients with severe symptomatic aortic stenosis (sSAS) who do not undergo treatment have an average lifespan of 1.8 years.

Human Burden

Aortic Stenosis

Prevalence of AS in Americans 75+

An estimated 12.4%, or ~2.5 million people ages 75+ in North America, have AS.

Age - A Major Risk Factor

Aortic Stenosis

Low detection rates for AS

Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.

Prevalence & Incidence

Related Facts

  • Undertreatment of patients with sSAS
    AS is often undertreated — one study found that 56% of severe symptomatic aortic stenosis (sSAS) patients referred to a cardiothoracic surgeon were not operated on.  
  • 2016 prevalence of Americans 65+ who had AVD
    In 2016, an estimated 5.2 million U.S. adults ages 65+ had aortic valve disease (AVD).   Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence estimates by Bach et al. 2007  
  • 2016 prevalence of aortic valve disease in America
    In 2016, as many as 5.8 million U.S. adults had aortic valve disease (AVD). Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence estimates by Bach et al. 2007  
  • Detection rate of heart murmurs
    More than 40% of heart murmurs — detected with a stethoscope and sometimes the first sign of heart valve disease (HVD) — are missed by family practitioners.  
  • Low detection rates for AS
    Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.