Silver Book Fact

Antiepileptic drugs relieve persistent neuropathic pain. One meta-analysis found gabapentin to be associated with moderate benefit (equivalent to 30% pain relief) in close to 1 in 2 patients, and a substantial benefit (equivalent to 50% pain relief) in close to 1 in 3 patients. Another meta-analysis found pregabalin effective in patients with postherpetic neuralgia, painful diabetic neuropathy, central neuropathic pain, and fibromyalgia.

Moore, R Andrew, Philip J Wiffen, Sheena Derry, and Henry J McQuay. Gabapentin for Chronic Neuropathic Pain and Fibromyalgia in Adults. Cochrane Database of Systematic Reviews. 2011; http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007938.pub2/abstract

Reference

Title
Gabapentin for Chronic Neuropathic Pain and Fibromyalgia in Adults
Publication
Cochrane Database of Systematic Reviews
Publication Date
2011
Authors
Moore, R Andrew, Philip J Wiffen, Sheena Derry, and Henry J McQuay
URL
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Categories

  • Innovative Medical Research
  • Human Value

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