Silver Book Fact

Effectiveness of an oral pharmacologic agent in preventing venous thrombosis

An oral pharmacologic agent has been demonstrated to be at least as effective as an injectable anticoagulant in the prevention of venous thrombosis following hip replacement.

Eriksson, BI, OE Dahl, N Rosencher, AA Kurth, CN van Dijk, SP Frostick, MH Prins, R Nettiarachchi, S Hantel, J Schnee, and HR Buller; for the RE-NOVATE Study Group. Dabigatran Etexilate Versus Enoxaparin for Prevention of Venous Thromboembolism After Total Hip- Replacement: A randomised, double-blind, non-inferiority trial. Lancet. 2007; 370(9591): 949-56. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2807%2961445-7/fulltext

Reference

Title
Dabigatran Etexilate Versus Enoxaparin for Prevention of Venous Thromboembolism After Total Hip- Replacement: A randomised, double-blind, non-inferiority trial
Publication
Lancet
Publication Date
2007
Authors
Eriksson, BI, OE Dahl, N Rosencher, AA Kurth, CN van Dijk, SP Frostick, MH Prins, R Nettiarachchi, S Hantel, J Schnee, and HR Buller; for the RE-NOVATE Study Group
Volume & Issue
Volume 370, Issue 9591
Pages
949-56
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • A study exploring the decline in deaths attributable to cardiovascular disease in the U.S. from 1980 to 2000 suggested that approximately 47% of the decrease was due to the increased…  
  • Trends in carotid endarterectomy procedures  
  • Total of physician office visits for first-listed stroke patients in 2014
    There were a total of 1,950,000 physician office visits in 2014 for patients first-listed for a stroke diagnosis.  
  • Death rates from heart disease have decreased from 586.6 deaths per 100,000 persons in 1950, to 240.8 deaths per 100,000 persons in 2002.  
  • If all untreated patients with Stage I or II hypertension had been treated and achieved normal blood pressures, there would have been 420,000 fewer hospital discharges in 2002 than actually…