Silver Book Fact

Direct thrombin inhibitor reduced relative risk of venous thromboembolism

An investigational direct thrombin inhibitor reduced relative risk of venous thromboembolism after total hip replacement surgery by 65.7%—compared to a currently available treatment.

Fuji, T et al. Efficacy and Safety of Edoxaban Verus Enoxaparin for the Prevention of Venous Thrombembolism Following Total Hip Arthroplasty: STARS J-V Trial. Orlando, Florida: American Society of Hematology,2010 Annual Meeting; December 4-7, 2010. http://ash.confex.com/ash/2010/webprogram/Paper29404.html

Reference

Title
Efficacy and Safety of Edoxaban Verus Enoxaparin for the Prevention of Venous Thrombembolism Following Total Hip Arthroplasty: STARS J-V Trial
Publisher
American Society of Hematology,2010 Annual Meeting
Publication Date
December 4-7, 2010
Authors
Fuji, T et al.
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • “Both echocardiography and nuclear imaging are used for provocative “stress” testing of the heart. When combined with exercise or other forms of stress such as administering inotropic or vasodilating drugs,…  
  • Effectiveness of treating ischemic stroke victims with rt-PA within 3 hours of symptom onset
    A study of the effectiveness of treating ischemic stroke victims with rt-PA within 3 hours of symptom onset found an estimated impact on long-term health outcomes of 564 quality-adjusted life-years saved…  
  • Stroke rates among Afib patients
    In one year, 58,283 of the 1.265 million Medicare beneficiaries with atrial fibrillation that did not receive prophylaxis suffered a stroke. For those who did receive anti-coagulants, 38,468 suffered strokes.  
  • There are 23 medicines in development for stroke, the third leading cause of death after heart disease and cancer.  
  • Between 1988 & 1994 and 1999 & 2004, use of pharmacological lipid-lowering treatment increased from 11.7% to 40.8%. Low-density lipoprotein cholesterol control increased from 4.0% to 25.1% among those with high…