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Prevalence of AS in Americans 75+

An estimated 12.4%, or ~2.5 million people ages 75+ in North America, have AS.

Osnabrugge R, Mylotte D, Head S, Van Meighem N, et al. Aortic Stenosis in the Elderly: Disease prevalence and number of candidates for transcathet aortic valve replacement, a meta-analysis and modeling study. Journal of the American College of Cardiology. September 10 2013. http://www.sciencedirect.com/science/article/pii/S0735109713020792. Accessed October 13, 2017

Reference

Title
Aortic Stenosis in the Elderly: Disease prevalence and number of candidates for transcathet aortic valve replacement, a meta-analysis and modeling study.
Publication
Journal of the American College of Cardiology
Publication Date
September 10 2013
Authors
Osnabrugge R, Mylotte D, Head S, Van Meighem N, et al.
Volume & Issue
Volume 62, Issue 11
URL
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Categories

  • Cost of Disease
  • Age - A Major Risk Factor

Publications

Aortic Stenosis Fact Sheet

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Connected Facts

Aortic Stenosis

2016 prevalence of aortic valve disease in America

In 2016, as many as 5.8 million U.S. adults had aortic valve disease (AVD).

Note: Alliance for Aging Research generated statistic, based on 2005 percentage prevalence
estimates by Bach et al. 2007

Prevalence & Incidence

Aortic Stenosis

Increased hospital admissions and prolonged length of stay for patients who do not undergo treatment

Medicare severe symptomatic aortic stenosis (sSAS) patients who do not undergo treatment have an average of 1.9 hospital admissions per year and prolonged lengths of stay — 11.5 hospital days per patient-year.

Human Burden

Aortic Stenosis

All-cause mortality for aortic valve disorders

In 2014, all-cause mortality for aortic valve disorders was 34,408 in the U.S.

Human Burden

Aortic Stenosis

1 and 6-month mortality rates without treatment for sSAS

Waiting for treatment for severe symptomatic aortic stenosis (sSAS) can be deadly, with 1-month mortality at 3.7% and 6-month mortality at 11.6% (measured from the time intervention was recommended).

Human Burden

Aortic Stenosis

Lifespan of Medicare patients with sSAS who do not undergo treatment

Medicare patients with severe symptomatic aortic stenosis (sSAS) who do not undergo treatment have an average lifespan of 1.8 years.

Human Burden

Aortic Stenosis

Low detection rates for AS

Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.

Prevalence & Incidence

Aortic Stenosis

Aortic stenosis impacts majority of heart valve disease patients

Aortic stenosis (AS) is among the most common forms of heart valve disease (HVD), affecting 2% to 3% of the adult U.S. population.

Prevalence & Incidence

Related Facts

  • Moderate or severe aortic valve disease is present in 4.2% to 10.7% of the population ages 65 and older.
     
  • Undertreatment of patients with sSAS
    AS is often undertreated — one study found that 56% of severe symptomatic aortic stenosis (sSAS) patients referred to a cardiothoracic surgeon were not operated on.  
  • All-cause mortality for aortic valve disorders
    In 2014, all-cause mortality for aortic valve disorders was 34,408 in the U.S.  
  • Low detection rates for AS
    Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.  
  • Survival rates of sSAS patients who do not undergo valve replacement
    Patients with severe symptomatic aortic stenosis (sSAS) who do not undergo valve replacement have survival rates as low as 50% at two years and 20% at 5 years after the…