Silver Book Fact

Prevalence of AS in Americans 75+

An estimated 12.4%, or ~2.5 million people ages 75+ in North America, have AS.

Osnabrugge R, Mylotte D, Head S, Van Meighem N, et al. Aortic Stenosis in the Elderly: Disease prevalence and number of candidates for transcathet aortic valve replacement, a meta-analysis and modeling study. Journal of the American College of Cardiology. September 10 2013. http://www.sciencedirect.com/science/article/pii/S0735109713020792. Accessed October 13, 2017

Reference

Title
Aortic Stenosis in the Elderly: Disease prevalence and number of candidates for transcathet aortic valve replacement, a meta-analysis and modeling study.
Publication
Journal of the American College of Cardiology
Publication Date
September 10 2013
Authors
Osnabrugge R, Mylotte D, Head S, Van Meighem N, et al.
Volume & Issue
Volume 62, Issue 11
URL
Read Full Resource

Categories

  • Cost of Disease
  • Age - A Major Risk Factor

Connected Facts

Related Facts

  • Moderate or severe aortic valve disease is present in 4.2% to 10.7% of the population ages 65 and older.
     
  • Undertreatment of patients with sSAS
    AS is often undertreated — one study found that 56% of severe symptomatic aortic stenosis (sSAS) patients referred to a cardiothoracic surgeon were not operated on.  
  • All-cause mortality for aortic valve disorders
    In 2014, all-cause mortality for aortic valve disorders was 34,408 in the U.S.  
  • Low detection rates for AS
    Prevalence estimates for AS are likely low. A U.K. population screening found previously undetected HVD in 1 in 2 adults ages 65+.  
  • Survival rates of sSAS patients who do not undergo valve replacement
    Patients with severe symptomatic aortic stenosis (sSAS) who do not undergo valve replacement have survival rates as low as 50% at two years and 20% at 5 years after the…