Silver Book Fact

After 9 years of tight blood pressure control, patients with type 2 diabetes had a 34% reduction in retinopathy progression and a 47% reduction in risk of visual acuity deterioration by three lines, when they had a 10/5 mmHg reduction in blood pressure.

Turner R, Holman R, Stratton I, Cull C, et al. Tight Blood Pressure Control and Risk of Macrovascular and Microvascular Complications in Type 2 Diabetes. BMJ. 1998; 317(7160): 703-13. http://www.bmj.com/cgi/content/abstract/317/7160/703

Reference

Title
Tight Blood Pressure Control and Risk of Macrovascular and Microvascular Complications in Type 2 Diabetes
Publication
BMJ
Publication Date
1998
Authors
Turner R, Holman R, Stratton I, Cull C, et al
Volume & Issue
Volume 317, Issue 7160
Pages
703-13
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • The ACCORD Eye Study found that combination lipid therapy with a fibrate and statin (compared with statin treatment alone) reduced progression of diabetic retinopathy in type 2 diabetics by around…  
  • After 9 years of tight blood pressure control, patients with type 2 diabetes had a 34% reduction in retinopathy progression and a 47% reduction in risk of visual acuity deterioration…  
  • Screening and treatment for diabetic retinopathy in type 2 diabetes patients produces annual savings of 53,986 person-years of sight.  
  • The NEI-sponsored Ocular Hypertensive Treatment Study (OHTS) found that lowering intraocular pressure (IOP) by at least 20% produced a 50% protective benefit for individuals who had an elevated IOP but…  
  • Nearly 50% of diabetic retinopathy patients who received ranibizumab–an anti-VEGF drug–experienced substantial visual improvement after a year of injections