Silver Book Fact

A systematic review of osteoporosis therapies found good evidence that many are effective in preventing fractures, but concluded that the data are insufficient to determine if any one therapy is better than the others.

MacLean C, Newberry S, Maglione M, McMahon M, et al. Systematic Review: Comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis. Annals of Internal Medicine. 2008; 148(3): 186-96. http://www.ncbi.nlm.nih.gov/pubmed/18087050

Reference

Title
Systematic Review: Comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis
Publication
Annals of Internal Medicine
Publication Date
2008
Authors
MacLean C, Newberry S, Maglione M, McMahon M, et al.
Volume & Issue
Volume 148, Issue 3
Pages
186-96
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Reducing secondary bone fractures can reduce medicare spending
    Reducing 5-20 percent of “secondary” bone fractures in 2015 could have reduced Medicare FFS spending by $310 million to $1.2 billion over a follow-up period that lasted up to 2 to…  
  • Alendronate, a bisphosphonate, has been shown to increase vertebral bone mineral density (BMD) by as much as 8% over 3-years in postmenopausal women with osteoporosis.  
  • Preventing Secondary Osteoporotic Fractures Yields Big Medicare Savings
     
  • An increase in bone mineral density (BMD) testing and osteoporosis treatment was associated with a decrease in hip fracture incidence.  
  • Risedronate, a bisphosphonate, has been shown to increase vertebral bone mineral density (BMD) by around 5% and hip BMD by 2% to 3% in postmenopausal women with osteoporosis.