Silver Book Fact

A meta-analysis of duloxetine, an anti-depressant, found a 50% reduction in pain at 12 weeks for diabetic peripheral neuropathy, and a 50% reduction in pain at 12 weeks for fibromyalgia.

Lunn M, Hughes R, Wiffen P. Duloxetine for Treating Painful Neuropathy or Chronic Pain. Cochrane Database of Systematic Reviews. 2009; 4. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007115.pub2/abstract

Reference

Title
Duloxetine for Treating Painful Neuropathy or Chronic Pain
Publication
Cochrane Database of Systematic Reviews
Publication Date
2009
Authors
Lunn M, Hughes R, Wiffen P
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • A proteasome inhibitor was found to reduce pain and joint destruction in an animal model of osteoarthritis, suggesting that nontoxic proteasome inhibitors could offer a novel pharmacotherapy option.  
  • The Mayo Clinic Pain Rehabilitation Center helps people with persistent pain return to an active lifestyle and has found that among patients who finish the program, nearly 84% report greater…  
  • Researchers have developed several sub-types of ion channels that allow inflammation and growth factors to trigger persistent pain.  
  • A meta-analysis of pscychological interventions for chronic low back pain found small but statistically significant effects for all interventions for as long as 5 years.  
  • Topical capsaicin was found in a meta-analysis to provide a degree of pain relief to some patients with painful neuropathic conditions.