Silver Book Fact

A meta-analysis of clinical trials found that calcium supplements reduced the risk of vertebral fractures by around 23%.

Shea B, Wells G, Cranney A, Zytaruk N, et al. Meta-Analysis of Calcium Supplementation for the Prevention of Postmenopausal Osteoporosis. Endocr Rev. 2002; 23(4): 552-9. http://edrv.endojournals.org/cgi/content/full/23/4/552

Reference

Title
Meta-Analysis of Calcium Supplementation for the Prevention of Postmenopausal Osteoporosis
Publication
Endocr Rev
Publication Date
2002
Authors
Shea B, Wells G, Cranney A, Zytaruk N, et al
Volume & Issue
Volume 23, Issue 4
Pages
552-9
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • An increase in bone mineral density (BMD) testing and osteoporosis treatment was associated with a decrease in hip fracture incidence.  
  • 30 drugs are currently in development for osteoporosis.  
  • Alendronate, a bisphosphonate, has been shown to increase vertebral bone mineral density (BMD) by as much as 8% over 3-years in postmenopausal women with osteoporosis.  
  • A recent study found that more postmenopausal women who took the drug denosumab gained at least 3% of bone mass at the hip and spine than those who took…  
  • Randomized controlled trials give evidence that pharmacologic therapy can reduce risk of fractures by 40 to 50%.