Silver Book Fact

A meta-analysis of clinical trials found that calcium supplements reduced the risk of vertebral fractures by around 23%.

Shea B, Wells G, Cranney A, Zytaruk N, et al. Meta-Analysis of Calcium Supplementation for the Prevention of Postmenopausal Osteoporosis. Endocr Rev. 2002; 23(4): 552-9. http://edrv.endojournals.org/cgi/content/full/23/4/552

Reference

Title
Meta-Analysis of Calcium Supplementation for the Prevention of Postmenopausal Osteoporosis
Publication
Endocr Rev
Publication Date
2002
Authors
Shea B, Wells G, Cranney A, Zytaruk N, et al
Volume & Issue
Volume 23, Issue 4
Pages
552-9
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Reducing risk of fracture from 8% to 2% reduces the 5-year fracture incidence from approximately 34% to 10%.  
  • Researchers are looking at the use of micro-computed tomography and magnetic resonance imaging to better understand the relationship between bone structure and fracture risk. Other tools are being evaluated for…  
  • Teriparatide, or human recombinant PTH, has been shown to decrease vertebral fractures by 65% to 69%, and non-vertebral fragility fractures by around 53%.  
  • A recent study found that more postmenopausal women who took the drug denosumab gained at least 3% of bone mass at the hip and spine than those who took…  
  • Reducing secondary bone fractures can reduce medicare spending
    Reducing 5-20 percent of “secondary” bone fractures in 2015 could have reduced Medicare FFS spending by $310 million to $1.2 billion over a follow-up period that lasted up to 2 to…