Silver Book Fact

A blood thinning drug was found to reduce the risk of heart attack, stroke, and cardiovascular disease by 20% in patients with acute coronary syndrome when given in addition to aspirin.

Yusuf S, Phil D, Zhao F, Mehta S, et al. Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation. N Engl J Med. 2001; 345(7): 494-502. http://content.nejm.org/cgi/content/abstract/345/7/494

Reference

Title
Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation
Publication
N Engl J Med
Publication Date
2001
Authors
Yusuf S, Phil D, Zhao F, Mehta S, et al.
Volume & Issue
Volume 345, Issue 7
Pages
494-502
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Cardiovascular disease death rates
    Cardiovascular disease accounts for nearly 801,000 deaths in the US, or about 1 of every 3 deaths in the US.  
  • A major objective is to control blood pressure and preempt primary and secondary stroke. Assessing specific antihypertensive therapies will identify specific treatments that will lower blood pressure.  
  • If all forms of cardiovascular disease were eliminated, life expectancy would rise by close to 7 years.  
  • Stroke rates among Afib patients
    In one year, 58,283 of the 1.265 million Medicare beneficiaries with atrial fibrillation that did not receive prophylaxis suffered a stroke. For those who did receive anti-coagulants, 38,468 suffered strokes.  
  • According to the Pharmaceutical Research and Manufacturers of America, 146 new medicines are being developed for heart disease and stroke. They include 17 for stroke, 16 for congestive heart failure,…