Thrombosis  /  Human Burden

Each year around 75,000 Americans are diagnosed with atrial fibrillation (AFib), 900,000 experience a venous thromboembolism event (VTE), and 800,000 have a stroke. The burden for those who survive is enormous and the cost of care a major expense for individuals and the nation. Fortunately research advances are offering significant hope. A number of investigative anticoagulants have the potential to reduce strokes in AFib patients while also reducing the risk of bleeds; clot-dissolving agents are proving to lessen the effects of strokes; and the same drugs in the pipeline for AFib could prevent VTE after major orthopedic surgery.

31 Matching Facts

Search matching Facts:
No results to display
    • Annual strokes from AFib
      Atrial fibrillation accounts for between 75,000 and 100,000 strokes per year.  
    • Atrial fibrillation increases stroke risk
      Atrial fibrillation increases the risk of stroke 5- fold.  
    • Atrial fibrillation on death certificates
      In 2008, atrial fibrillation was mentioned on 99,294 death certificates in the U.S. and was the underlying cause of death in 15,383.  
    • Effect of hip and knee replacement surgeries on risk of VTE
      Hip and knee replacement surgeries significantly raise the risk of venous thromboembolism—without prophylaxis around half develop deep vein thrombosis and 1% to 2% develop pulmonary embolism.  
    • Average length of stay in intensive care for VTE patients after surgery
      The mean length of stay in the intensive care unit for patients hospitalized after major orthopedic surgery  was roughly ten times longer for patients who developed venous thromboembolism.  
    • Average length of hospital stay for VTE patients after surgery
      The mean length of stay for patients hospitalized after major orthopedic surgery was more than twice as  long for patients with venous thromboembolism (VTE)—as compared to those without VTE. VTE…  
    • Venous thromboembolism hospitalization rates
      An estimated 250,000 patients are hospitalized each year with venous thromboembolism.  
    • Venous thromboembolism (VTE) outcomes
      Of the more than 200,000 new cases of venous thromboembolism (VTE) that occur each year, 30% die within 30 days, 20% suffer a sudden death from pulmonary embolism, and around…  
    • Symptomatic venous thromboembolism outcomes
      Around one-third of patients with symptomatic venous thromboembolism manifest pulmonary embolism. Two-thirds manifest deep vein thrombosis alone. Death occurs within 1 month of diagnosis in approximately 6% of deep vein…  
    • Venous thromboembolism in the community
      More than 50% of all cases of venous thromboembolism in the community can be attributed to institutionalization.  
    • Undetected pulmonary embolism
      More than 59% of the 300,000 people who die from venous thromboembolism in the U.S. each year have undetected pulmonary embolism.  
    • In-hospital deaths caused by venous thromboembolism
      The number of in-hospital deaths that are caused by venous thromboembolism is more than five times the number of deaths caused by all hospital-acquired infections.  
    • Venous thromboembolism in hospital mortality rate
      About 1 in 8 patients who develop venous thromboembolism in the hospital will die as a result.  
    • Venous thromboembolism mortality rate
      Venous thromboembolism causes an estimated 300,000 deaths each year.  
    • Depression and anxiety in AFib patients
      Around 1/3 of atrial fibrillation patients have elevated levels of depression and anxiety.  
    • Hospital readmission rates among AFib patients
      In the year following initial hospitalization for atrial fibrillation (AF), 12.5% of chronic AF patients were readmitted for AF—17.6% of readmissions occurred within 1 month. Among newly-diagnosed patients, 10.1% were…  
    • AFib patient hospital visits
      Individuals with atrial fibrillation (AF) are 4 times more likely to visit the hospital 3 or more times in the year following an AF diagnosis—compared to those without the disease.  
    • Medical care rates during the year following an AFib diagnosis
      A study of Medicare beneficiaries found that during the year following an atrial fibrillation (AF) diagnosis: • 28% of AF patients (versus 7% of non-AF patients) had 3 or more hospital…  
    • Medical care associated with atrial fibrillation, 2001
      In 2001, atrial fibrillation was the cause of around: • 350,000 hospitalizations • 5 million office visits • 276,000 emergency department visits • 234,000 out-patient visits  
    • AFib strokes occurring in patients 75+
      Close to half of all atrial fibrillation associated strokes occur in patients age 75 and older.  
    • The risk of stroke attributable to atrial fibrillation by age
      The risk of stroke attributable to atrial fibrillation increases from 1.5% for those ages 50 to 59 to 23.5% for those ages 80 to 89.  
    • Atrial fibrillation stroke risk
      Atrial fibrillation (AF) increases the risk of severe and recurrent ischemic stroke. Patients not treated with anticoagulants have a 2.1-fold increase in risk of recurrent stroke and 2.4-fold increase in…  
    • Ischemic strokes caused by AFib
      Atrial fibrillation is responsible for at least 15% to 20% of all ischemic strokes.  
    • Risk of ischemic stroke in AFib patients
      The risk of ischemic stroke in nonvalvular atrial fibrillation patients is 2 to 7 times (200% to 700%) greater than in those without the disease.  
    • Heart failure rates among AFib patients
      A study of Medicare beneficiaries found that those with atrial fibrillation (AF) were significantly more likely to experience heart failure than their non-AF counterparts (36.7% versus 10.4%).  
    • Primary diagnoses for AFib patients
      Heart failure was listed as the primary diagnosis for 11.8% of patients hospitalized with atrial fibrillation (AF). Coronary heart disease was listed for 9.9% of AF patients, and stroke was…  
    • Most common causes of death after AFib diagnosis
      Within the first 4 months of diagnosis of atrial fibrillation, the most common cause of cardiovascular deaths are coronary artery disease (22%), heart failure (14%), and ischemic stroke (10%). After…  
    • Medicare beneficiaries AFib mortality rate
      Of Medicare beneficiaries who receive an atrial fibrillation diagnosis, 1 in 4 will die within a year.  
    • Atrial fibrillation doubles mortality risk
      Atrial fibrillation is associated with an approximate doubling of mortality risk.  
    • Atrial fibrillation as a contributory cause of death
      Around 84% of all deaths with atrial fibrillation as a contributory cause are in individuals age 75 and older.  
    • Atrial fibrillation as a contributory cause of death, 2011
      Atrial fibrillation is a contributory cause of death for around 93,000 Americans each year.