Healthcare-Associated Infections  /  Innovative Medical Research

Healthcare-associated infections (HAIs) are acquired while receiving medical or surgical care for other conditions in hospitals, physician offices, long-term care facilities, and other healthcare settings. They are largely preventable, yet often costly and deadly, and rapidly becoming a national crisis as they increasingly develop resistance to drugs.

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    • Negative value of antibiotics to drug companies
      The value of an antibiotic to a drug company is negative $50 million- compared to the positive value of $1 billion for a new musculoskeletal drug.  
    • New antibacterial agents between 1983 and 2012
      Total number of new antibacterial agents is in decline  
    • Infection control program reduced hospital-acquired HAIs by > 1/3
      A multimodal infection control program reduced the rate of hospital-acquired HAIs by more than 1/3 and improved quality of care and patient outcomes.  
    • Reduction of central-line infections saved ~ 1,800 lives and $280 million
      Standardization of best practice interventions reduced central line-associated blood stream infections and saved an estimated 1,800 lives and $280 million.  
    • Over 8 years infection control practices saved ~27,000 lives and $1.8 billion
      Infection control practices saved an estimated 27,000 lives and $1.8 billion in medical costs between 2001 and 2009.  
    • An antibiotic stewardship program saved $17 million over 8 years
      An antibiotic stewardship program saved a total of $17 million over 8 years, with antibiotic costs rising $1 million in the first year after discontinuation.  
    • Pre-surgery antibiotic use reduces 6-day mortality by 50% in elderly
      Effective pre-surgery antibiotic use can reduce 60-day mortality in the elderly by 50%.  
    • Only a 20% reduction in drug-resistant infections would save $3.2 – $5.2 billion each year
      A 20% reduction in drug-resistant infections would save between 5.7 and 11.3 million additional hospital days and between $3.2 and $5.2 billion in healthcare costs, each year.  
    • Reduction in hospital-acquired HAIs could produce significant savings
      Practices that lead to a 20% reduction in preventable hospital-acquired HAIs would save up to $6.8 billion in medical costs. a 70% reduction would lead to a savings of up…