Silver Book publication

Aortic Stenosis Fact Sheet

Aortic stenosis is one of the most common and serious types of heart valve disease. Aortic stenosis can be
debilitating, costly, and deadly. Survival rates without treatment for severe symptomatic aortic stenosis are low at 50% at 2 years after symptom onset, and 20% at 5 years. Fortunately, innovative treatments are saving lives and aortic stenosis can be successfully treated with valve replacement in patients of all ages.

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    • Cost-effectiveness of TAVR in sSAS patients
      Patients with severe symptomatic aortic stenosis (sSAS) considered to be at high surgical risk who underwent transcatheter aortic valve replacement (TAVR) experienced lifetime incremental cost-effectiveness ratios of $55,090 per QALY…  
    • Cost-effectiveness of SAVR
      The cost-effectiveness ratio for surgical aortic valve replacement (SAVR), compared to no surgery, was estimated at $13,528 per quality-adjusted life year (QALY) (~$17,225 in 2017 dollars).  
    • Life expectancy and quality of life gains from AVR
      A study of 4,617 patients who underwent aortic valve replacement (AVR) over a period of 20 years found significant gains in life expectancy and quality of life — 43,166 net life-years…  
    • Disease specific status and generic health status improvements from TAVR and SAVR
      Transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in intermediate risk symptomatic aortic stenosis (SAS) patients were associated with significant improvements in disease specific status (16 to…  
    • Satisfaction with HVD Treatment
      Among treated heart valve disease (HVD), 96% express “full satisfaction” and 78% are “very satisfied” with their treatment.