Silver Book Fact

Topical NSAIDs were found in a meta-analysis to be significantly more effective than placebo in reducing persistent pain from musculoskeletal conditions.

Derry S, Moore R, Rabbie R. Topical NSAIDs for Chronic Musculoskeletal Pain in Adults. Cochrane Database of Systemic Reviews. 2012; http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007400.pub2/abstract;jsessionid=59B047BE4B4F53FCE12F2A8B0DFFF782.d03t02?deniedAccessCustomisedMessage=&userIsAuthenticated=false

Reference

Title
Topical NSAIDs for Chronic Musculoskeletal Pain in Adults
Publication
Cochrane Database of Systemic Reviews
Publication Date
2012
Authors
Derry S, Moore R, Rabbie R
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • 60% of people with persistent back pain who turned to complementary and alternative medicine perceived a “”great deal”” of benefit.  
  • Understanding the role of genetics in pain mechanisms is increasing and the potential now exists to conduct genome-wide screens in model organisms to look for pain-associated genes.  
  • An opiate agonist often used for persistent pain, tramadol was found in one meta-analysis to significantly reduce neuropathic pain when compared to placebo.  
  • Brain imaging is showing that pain changes the structure and function of brain regions that perceive pain, making it persistent. These brain networks and receptor targets are being identified…  
  • Researchers have discovered that some types of glial cells have a major impact on persistent neuropathic pain and that targeting these cells may result in a new class of disease…