Silver Book Fact

TAVR v. SAVR in Intermediate-Risk SAS Patients

At 1-year, severe aortic stenosis (SAS) patients with intermediate surgical mortality risk who underwent transcatheter aortic valve replacement (TAVR), had all-cause mortality rates of 7.4% (compared to 13% for surgical aortic valve replacement (SAVR)), disabling stroke rates of 2.3% (compared to 5.9% for SAVR), and rehospitalization rates of 11.4% (compared to 15.1% for SAVR).

Thourani V, Kodali S, Makkar R, et al. Transcatheter Aortic Valve Replacement Versus Surgical Valve Replacement in Intermediate-Risk Patients: A propensity score analysis. Lancet. 2016; 387(10034): 2218-25. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)30073-3/references

Reference

Title
Transcatheter Aortic Valve Replacement Versus Surgical Valve Replacement in Intermediate-Risk Patients: A propensity score analysis
Publication
Lancet
Publication Date
2016
Authors
Thourani V, Kodali S, Makkar R, et al
Volume & Issue
Volume 387, Issue 10034
Pages
2218-25
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • TAVR Success in sSAS Patients
    A study of severe symptomatic aortic stenosis (sSAS) patients who received transcatheter aortic valve replacement (TAVR) found 30-day mortality of 2.2% for those who were high risk of surgical mortality/inoperable,…  
  • Survival rates of SAS patients ages 80+ with and without SAVR
     
  • Survival Rates of SAS Patients with and without SAVR
    Patients with severe aortic stenosis (SAS) ages 80+ who underwent surgical aortic valve replacement (SAVR) have 1-year, 2-year, and 5-year survival rates of 87%, 78%, and 68% respectively — compared with…  
  • Cost-effectiveness of TAVR in sSAS patients
    Patients with severe symptomatic aortic stenosis (sSAS) considered to be at high surgical risk who underwent transcatheter aortic valve replacement (TAVR) experienced lifetime incremental cost-effectiveness ratios of $55,090 per QALY…  
  • Improvements in QoL from TAVR in SAS patients
    Symptomatic aortic stenosis (SAS) patients who underwent transcatheter aortic valve replacement (TAVR) experienced quality of life (QoL) improvements from 5.3 at baseline (10 point scale with 10=best imaginable health state)…