Silver Book Fact

Subthalamic nuclei deep brain stimulation (STN-DBS) raises pain thresholds in Parkinson’s disease patients.

Dellapina E, Ory- Magne F, Regragui W, et al. Effect of Subthalamic Deep Brain Stimulation in Parkinson’s Disease. Pain. 2012; 153(11): 2267-73. http://www.painjournalonline.com/article/S0304-3959(12)00453-8/abstract

Reference

Title
Effect of Subthalamic Deep Brain Stimulation in Parkinson’s Disease
Publication
Pain
Publication Date
2012
Authors
Dellapina E, Ory- Magne F, Regragui W, et al
Volume & Issue
Volume 153, Issue 11
Pages
2267-73
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Researchers have developed several sub-types of ion channels that allow inflammation and growth factors to trigger persistent pain.  
  • Opioids have been found to reduce pain intensity and improve physical functioning for patients with persistent noncancer pain. It’s important to note that a decrease in mental health functioning…  
  • Subthalamic nuclei deep brain stimulation (STN-DBS) raises pain thresholds in Parkinson’s disease patients.  
  • Topical NSAIDs were found in a meta-analysis to be significantly more effective than placebo in reducing persistent pain from musculoskeletal conditions.  
  • Use of stem cells to create neurons could enable the study of the response of human cells to new drugs in vitro, early in the drug development process.