Silver Book Fact

Statin use in mouse models show pain-alleviating effects for neuropathic pain.

Shi, Xiang Qun, Tony KY Lim, Seunghwan Lee, Yuan Qing Zhao, and Ji Zhang. Statins Alleviate Experimental Nerve-Injury Induced Neuropathic Pain. Pain. 2011; 152(5): 1033-43. https://insights.ovid.com/pubmed?pmid=21414721

Reference

Title
Statins Alleviate Experimental Nerve-Injury Induced Neuropathic Pain
Publication
Pain
Publication Date
2011
Authors
Shi, Xiang Qun, Tony KY Lim, Seunghwan Lee, Yuan Qing Zhao, and Ji Zhang
Volume & Issue
Volume 152, Issue 5
Pages
1033-43
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Understanding the role of genetics in pain mechanisms is increasing and the potential now exists to conduct genome-wide screens in model organisms to look for pain-associated genes.  
  • Resolvins, a family of lipid mediators, have shown potential in resolving persistent inflammatory pain.  
  • Exercise has shown to be effective in reducing persistent pain from osteoarthritis of the knee.  
  • 57% of American adults say they would pay an extra $1 per week in taxes in order to support government research into the causes of and treatment for chronic pain.  
  • An opiate agonist often used for persistent pain, tramadol was found in one meta-analysis to significantly reduce neuropathic pain when compared to placebo.