Silver Book Fact

Researchers have developed several sub-types of ion channels that allow inflammation and growth factors to trigger persistent pain.

Institute of Medicine; Committee on Advancing Pain Research, Care and Education. Relieving Pain in America: A blueprint for transforming prevention, care, education, and research. Washington, DC: National Academies Press; 2011. http://www.iom.edu/Reports/2011/Relieving-Pain-in-America-A-Blueprint-for-Transforming-Prevention-Care-Education-Research.aspx

Reference

Title
Relieving Pain in America: A blueprint for transforming prevention, care, education, and research
Publisher
National Academies Press
Publication Date
2011
Authors
Institute of Medicine; Committee on Advancing Pain Research, Care and Education
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Topical clonidine gel significantly reduces foot pain in patients with painful diabetic neuropathy.  
  • In individuals with persistent low back pain, tanezumab, a humanized anti-nerve growth factor antibody, showed clinical and statistical analgesic efficacy that was superior to placebo and naproxen.  
  • Topical capsaicin was found in a meta-analysis to provide a degree of pain relief to some patients with painful neuropathic conditions.  
  • An oral cannabinoid was found effective in relieving diabetic peripheral neuropathic pain symptoms and improving disturbed sleep, quality of life, and overall patient status.  
  • Brain imaging is showing that pain changes the structure and function of brain regions that perceive pain, making it persistent. These brain networks and receptor targets are being identified…