Silver Book Fact

Patients with vertebral fractures who underwent kyphoplasty, a procedure that stabilizes fractures of the spine, were found in one study to have reduced pain, fewer new fractures, and less healthcare utilization for at least 12 months.

Grafe I, Da Fonseca K, Hilmeier J, et al. Reduction of Pain and Fracture Incidence After Kyphoplasty: 1-year outcomes of a prospective controlled trial of patients with primary osteoporosis. Osteoporos Int. 2005; 16(12): 2005-12. http://www.springerlink.com/content/q235u1m804u08551/?p=34936217d13e479297297d5ff7202c45&pi=72

Reference

Title
Reduction of Pain and Fracture Incidence After Kyphoplasty: 1-year outcomes of a prospective controlled trial of patients with primary osteoporosis
Publication
Osteoporos Int
Publication Date
2005
Authors
Grafe I, Da Fonseca K, Hilmeier J, et al
Volume & Issue
Volume 16, Issue 12
Pages
2005-12
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Genetics can account for up to 75% of bone mineral density (BMD). Researchers have identified a gene that strongly influences peak bone mass in mice. The gene was not previously…  
  • Raloxifene, a selective estrogen receptor modulator (SERM), has been shown to decrease vertebral fractures by up to 50% after 3 years.  
  • An increase in bone mineral density (BMD) testing and osteoporosis treatment was associated with a decrease in hip fracture incidence.  
  • Risedronate, a bisphosphonate, has been shown to increase vertebral bone mineral density (BMD) by around 5% and hip BMD by 2% to 3% in postmenopausal women with osteoporosis.  
  • Randomized controlled trials give evidence that pharmacologic therapy can reduce risk of fractures by 40 to 50%.