Silver Book Fact

Initiating and continuing beta-blocker use in most first-time heart attack survivors for 20 years would result in 72,000 fewer coronary heart disease deaths, 62,000 fewer heart attacks, and 447,000 gained life-years. Additionally, it would save up to $18 million.

Phillips, Kathryn A., Michael G. Shlipak, Pamela Coxson, Paul A. Heidenreich, Myriam G. Hunink, Paula A. Goldman, Lawrence W. Williams, Milton C. Weinstein, and Lee Goldman. Health and Economic Benefits of Increased Beta-Blocker Use Following Myocardial Infarction. JAMA. 2000; 284(21): 2748-54. http://jama.ama-assn.org/cgi/content/abstract/284/21/2748

Reference

Title
Health and Economic Benefits of Increased Beta-Blocker Use Following Myocardial Infarction
Publication
JAMA
Publication Date
2000
Authors
Phillips, Kathryn A., Michael G. Shlipak, Pamela Coxson, Paul A. Heidenreich, Myriam G. Hunink, Paula A. Goldman, Lawrence W. Williams, Milton C. Weinstein, and Lee Goldman
Volume & Issue
Volume 284, Issue 21
Pages
2748-54
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Antihypertensive therapy has been associated in clinical trials with a 1/3 reduction in stroke incidence, a 1/4 reduction in myocardical infarctions and a more than 1/2 reduction in heart failure.  
  • From approval in 2011 through 2015 >54,000 TAVRs were performed in 418 centers in 48 states
     
  • Between 1988 & 1994 and 1999 & 2004, use of pharmacological lipid-lowering treatment increased from 11.7% to 40.8%. Low-density lipoprotein cholesterol control increased from 4.0% to 25.1% among those with high…  
  • In 2005, approximately 469,000 coronary artery bypass procedures were performed on 261,000 patients in the U.S.  
  • Aspirin use in AFib patients
    Meta-analysis of a number of randomized controlled trials found that aspirin use in atrial fibrillation patients reduced stroke risk by an average 22%.